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To determinate the effect of drinking alcohol on the permeability of capillary in gingival tissue, thirty one male subjects ; 19 to 25 years old, with general health and no missing teeth except third molar were selected from volunteers of dental students of Chosun University. 20 per body weight (kg) of distilled water, 25% and 40% ethanol were orally administered to selected subjects at regular one-week interval. The amount of gingival c revicular fluid of upper right first molar and lower left central incisor was measured by PERIOTRON (HARCO Electronics, Canada) from 30 minutes to 6 hours after administration of each experimental solution, and blood pressure, pulse rate and body temperature were subsequently checked. Each score change between before and after administration of experimental solution was statistically analyzed by student t-test and ANOVA The following results were obtained 1. Regardless of concentration of alcohol and severity of gingival inflammation, the amount of gingival crevicular fluid was increased in maximum value at 2 hour after administration, gradually reduced by time passed, and in 6 hours finally returned to the baseline value. 2. In posterior tooth than anterior tooth, the amount of gingival crevicular fluid was increased in greater extent and the returning time to baseline value was prolonged. a The effect of drinking alcohol on the permeability of gingival sulcular epithelium was earlier and longer in healthy gingiva than inflamed gingiva 4. Both systolic and diastolic blood pressure were not influenced by alcohol drinking (p>0.1), regardless of alcohol concentration. 5. By 2-hour after alcohol drinking, both pulse rate (p<0.01), and body temperature (p.<0.01) were significantly increased. 6. The effects of drinking alcohol on gingival crevicular fluid, pulse rate, and body temperature were persisted longer in higher concentration of alcohol.
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